Richard K Bogan Selected Research

Sodium Oxybate (gamma Hydroxybutyrate)

1/2022	Changes in Cataplexy Frequency in a Clinical Trial of Lower-Sodium Oxybate with Taper and Discontinuation of Other Anticataplectic Medications.
1/2022	Calcium, Magnesium, Potassium, and Sodium Oxybates Oral Solution: A Lower-Sodium Alternative for Cataplexy or Excessive Daytime Sleepiness Associated with Narcolepsy.
1/2022	Safety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia: a phase 3, placebo-controlled, double-blind, randomised withdrawal study.
12/2021	Efficacy and safety of calcium, magnesium, potassium, and sodium oxybates (lower-sodium oxybate [LXB]; JZP-258) in a placebo-controlled, double-blind, randomized withdrawal study in adults with narcolepsy with cataplexy.
11/2021	Corrigendum to: Efficacy and safety of calcium, magnesium, potassium, and sodium oxybates (lower-sodium oxybate [LXB]; JZP-258) in a placebo-controlled, double-blind, randomized withdrawal study in adults with narcolepsy with cataplexy.
7/2021	Corrigendum to: Efficacy and Safety of Calcium, Magnesium, Potassium, and Sodium Oxybates (Lower-Sodium Oxybate [LXB]; JZP-258) in a Placebo-Controlled, Double-Blind, Randomized Withdrawal Study in Adults With Narcolepsy With Cataplexy.
1/2020	Update on the pharmacologic management of narcolepsy: mechanisms of action and clinical implications.
12/2017	Correlation of Changes in Patient-Reported Quality of Life With Physician-Rated Global Impression of Change in Patients With Narcolepsy Participating in a Clinical Trial of Sodium Oxybate: A Post Hoc Analysis.
4/2015	Time to response with sodium oxybate for the treatment of excessive daytime sleepiness and cataplexy in patients with narcolepsy.
6/2009	Weight loss in narcolepsy patients treated with sodium oxybate.

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Richard K Bogan Research Topics

Disease

14	Narcolepsy 01/2022 - 09/2003
9	Cataplexy 01/2022 - 06/2009
8	Sleepiness 09/2015 - 09/2003
6	Obstructive Sleep Apnea 01/2020 - 04/2010
6	Restless Legs Syndrome (Restless Legs) 05/2015 - 01/2006
4	Disorders of Excessive Somnolence (Hypersomnia) 01/2022 - 01/2006
2	Nausea 09/2015 - 07/2010
2	Headache (Headaches) 09/2015 - 07/2010
1	Sleep Wake Disorders 01/2022
1	Idiopathic Hypersomnia 01/2022
1	Pain (Aches) 05/2015
1	Apnea 09/2013
1	Sleep Apnea Syndromes (Sleep Apnea) 09/2013
1	Dizziness (Lightheadedness) 09/2011
1	Diarrhea 07/2010
1	Circadian Rhythm Sleep Disorders (Delayed Sleep Phase Syndrome) 07/2010
1	Jet Lag Syndrome 07/2010
1	Airway Obstruction (Choking) 06/2010
1	Weight Loss (Weight Reduction) 06/2009
1	Insulin Resistance 12/2008
1	Sleep Initiation and Maintenance Disorders (Insomnia) 09/2008

Drug/Important Bio-Agent (IBA)

10	Sodium Oxybate (gamma Hydroxybutyrate)FDA Link 01/2022 - 06/2009
5	Modafinil (Provigil)FDA Link 01/2020 - 09/2003
4	PotassiumIBA 01/2022 - 07/2021
4	MagnesiumIBA 01/2022 - 07/2021
4	CalciumIBA 01/2022 - 07/2021
4	SodiumIBA 01/2022 - 07/2021
4	solriamfetolIBA 01/2020 - 09/2015
3	Antidepressive Agents (Antidepressants)IBA 01/2022 - 09/2008
3	1- (((alpha- isobutanoyloxyethoxy)carbonyl)aminomethyl)- 1- cyclohexaneacetic acidIBA 05/2015 - 06/2010
2	SolutionsIBA 01/2022 - 01/2022
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2020 - 01/2020
2	ropinirole (Requip)FDA LinkGeneric 03/2008 - 01/2006
1	Wakefulness-Promoting AgentsIBA 01/2020
1	pitolisantIBA 01/2020
1	AmphetaminesIBA 01/2020
1	Dopamine (Intropin)FDA LinkGeneric 01/2020
1	Histamine (Histamine Dihydrochloride)FDA Link 01/2020
1	Methylphenidate (Ritalin)FDA LinkGeneric 01/2020
1	Serotonin (5 Hydroxytryptamine)IBA 01/2020
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	rotigotine FDA Link 03/2014
1	Pharmaceutical PreparationsIBA 06/2010
1	Glucose (Dextrose)FDA LinkGeneric 12/2008
1	Histamine Antagonists (Antihistamines)IBA 09/2008
1	Zolpidem (Ambien)FDA LinkGeneric 09/2008
1	Butyric Acid (Butanoic Acid)IBA 09/2008
1	Melatonin Receptors (Melatonin Receptor)IBA 09/2008
1	Hypnotics and Sedatives (Sedatives)IBA 09/2008
1	Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone (FCCP)IBA 02/2007
1	Dopamine Agonists (Dopamine Agonist)IBA 01/2006

Therapy/Procedure

2	Continuous Positive Airway Pressure 01/2017 - 09/2013
2	Therapeutics 09/2013 - 04/2010
1	Electrodes (Electrode) 09/2013
1	Complementary Therapies (Alternative Medicine) 09/2008